Bin Chen

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer et al. · Cell Reports · 2016 · 784 citations · Full text

Gene Deletion Data, Genetics, Acute Myeloid Leukemia +9

Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial

Rury R. Holman, Ruth L. Coleman, Juliana C.N. Chan et al. · The Lancet Diabetes & Endocrinology · 2017 · 316 citations

Metabolic Syndrome, Glucose Tolerance, Diabetes Management +10

The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis

Guangsi Shen, Haibin Zhou, Hong Zhang et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2018 · 113 citations

Metabolic Syndrome, Bone Health, Health Sciences +15

Iron-induced oxidative stress stimulates osteoclast differentiation via NF-κB signaling pathway in mouse model

Xiao Wang, Bin Chen, Jingyue Sun et al. · Metabolism · 2018 · 108 citations

Inflammation, Iron Metabolism, Cell Signaling +10

The Histamine H4 Receptor Antagonist, JNJ 39758979, Is Effective in Reducing Histamine-Induced Pruritus in a Randomized Clinical Study in Healthy Subjects

Alexa P. Kollmeier, Klaus Francke, Bin Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 86 citations