Bin Chen

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer et al. · Cell Reports · 2016 · 834 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial

Rury R. Holman, Ruth L. Coleman, Juliana C.N. Chan et al. · The Lancet Diabetes & Endocrinology · 2017 · 320 citations

Medicine, Cardiology, Pharmacology +16

The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis

Guangsi Shen, Haibin Zhou, Hong Zhang et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2018 · 115 citations

Medicine, Biochemistry, Molecular Biology +16

Iron-induced oxidative stress stimulates osteoclast differentiation via NF-κB signaling pathway in mouse model

Xiao Wang, Bin Chen, Jingyue Sun et al. · Metabolism · 2018 · 112 citations

Life Sciences, Cell Biology, Molecular Biology +14

Dihydroartemisinin ameliorates LPS-induced neuroinflammation by inhibiting the PI3K/AKT pathway

Yuting Gao, Miao-Miao Cui, Sijin Zhong et al. · Metabolic Brain Disease · 2020 · 87 citations

Life Sciences, Neuroscience, Pharmacology +13