Jianjun Chen

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

Huilin Huang, Hengyou Weng, Wenju Sun et al. · Nature Cell Biology · 2018 · 3K citations · Full text

Engineering, Rna Binding Proteins, Mrna Stability +10

FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase

Zejuan Li, Hengyou Weng, Rui Su et al. · Cancer Cell · 2016 · 1.6K citations · Full text

N 6, Chromatin, Natural Sciences +10

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Rui Su, Lei Dong, Chenying Li et al. · Cell · 2017 · 1.2K citations · Full text

Tumor Biology, Medicine, Tumor Suppressor +3

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

Hengyou Weng, Huilin Huang, Huizhe Wu et al. · Cell stem cell · 2017 · 993 citations · Full text

Hematological Malignancy, Medicine, Mixed-phenotype Acute Leukemia +9

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia

Yue Huang, Rui Su, Yue Sheng et al. · Cancer Cell · 2019 · 825 citations · Full text

Hematological Malignancy, Biochemistry, Natural Sciences +8