Sparse whole-genome sequencing identifies two loci for major depressive disorder

Na Cai, Tim B. Bigdeli, Warren W. Kretzschmar, +102

Nature

Genome-wide Association StudyPsychiatryGeneticsPsychiatric GeneticsDepression +5

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

Gang Wang, Megan L. McCain, Luhan Yang, +25

Nature Medicine

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

Jem Efe, Simon Hilcove, Janghwan Kim, +5

Nature Cell Biology

Regenerative MedicineTissue EngineeringCardiac MuscleInduced Pluripotent Stem CellCardiac Reprogramming +11

Adult mouse epicardium modulates myocardial injury by secreting paracrine factors

Bin Zhou, Leah Honor, Huamei He, +17

Journal of Clinical Investigation

Cardiac MuscleHeart FailureEpdc-conditioned MediumCardiac Progenitor CellsCardiovascular Toxicity +15

Generation of Functional Human Hepatic Endoderm From Human Induced Pluripotent Stem Cells

Gareth J. Sullivan, David C. Hay, In-Hyun Park, +14

Hepatology

mir-17–92 Cluster Is Required for and Sufficient to Induce Cardiomyocyte Proliferation in Postnatal and Adult Hearts

Jinghai Chen, Zhan‐Peng Huang, Heeyoung Seok, +9

Circulation Research

PRC2 directly methylates GATA4 and represses its transcriptional activity

Aibin He, Xiaohua Shen, Qing Ma, +7

Genes & Development

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationEpigenetics +14

HCN4 Dynamically Marks the First Heart Field and Conduction System Precursors

Xingqun Liang, Gang Wang, Lizhu Lin, +7

Circulation Research

DNMT1-mediated methylation of BEX1 regulates stemness and tumorigenicity in liver cancer

Qian Wang, Ning Liang, Tao Yang, +11

Journal of Hepatology

Tumor BiologyDnmt1-mediated MethylationLineage PlasticityMedicineEpigenetic Change +8

Optimization of Genome Engineering Approaches with the CRISPR/Cas9 System

Kai Li, Gang Wang, Troels Andersen, +2

PLoS ONE

Crispr/cas9 SystemEngineeringGenome SurgeryDesigner NucleasesGenetics +12