Yang Chen

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

A candidate prostate cancer susceptibility gene at chromosome 17p

Sean V. Tavtigian, Jacques Simard, David H.F. Teng et al. · Nature Genetics · 2001 · 555 citations

Medicine, Genetics, Molecular Genetics +11

Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation

Yuying Liu, Xiaoyu Liang, Wenqian Dong et al. · Cancer Cell · 2018 · 522 citations

Life Sciences, Immunology, Oncology +16

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription

Rui Xiao, Jiayu Chen, Zhengyu Liang et al. · Cell · 2019 · 419 citations · Full text

Life Sciences, Genetics, Molecular Biology +10

MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion

Yu-Lu Cao, Shuxia Meng, Yang Chen et al. · Nature · 2017 · 329 citations

Life Sciences, Cell Biology, Molecular Biology +12