Jianfeng Chen

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao, Lewis Z. Shi, Hao Zhao et al. · Cell · 2016 · 1.3K citations · Full text

Tumor Biology, Cancer Immunosurveillance, Medicine +10

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

Jianjun Gao, John F. Ward, Curtis A. Pettaway et al. · Nature Medicine · 2017 · 583 citations · Full text

Ipilimumab Therapy, Medicine, Immunology +7

Allogeneic CD19-targeted CAR-T therapy in patients with severe myositis and systemic sclerosis

Xiaobing Wang, Binghe Tan, Liang Zhu et al. · Cell · 2024 · 215 citations

Severe Myositis, Autoimmune Disease, Systemic Treatment +9

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

Guangchun Han, Guoliang Yang, Dapeng Hao et al. · Nature Communications · 2021 · 208 citations · Full text

Runx2-Upregulated Receptor Activator of Nuclear Factor κB Ligand in Calcifying Smooth Muscle Cells Promotes Migration and Osteoclastic Differentiation of Macrophages

Chang Hyun Byon, Yong Sun, Jianfeng Chen et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2011 · 165 citations