Jijie Gu

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Chengbin Wu, Ying Hua, Christine Grinnell et al. · Nature Biotechnology · 2007 · 334 citations

Systems Biology, Engineering, Allergy +11

The Bcl-2 Family Antagonist ABT-737 Significantly Inhibits Multiple Animal Models of Autoimmunity

Philip D. Bardwell, Jijie Gu, Donna McCarthy et al. · The Journal of Immunology · 2009 · 69 citations

Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

Clarissa G. Jakob, Rohinton Edalji, Russell A. Judge et al. · mAbs · 2013 · 65 citations · Full text

Inner Variable Domain, Immunology, Immune Regulation +24

ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models

Yingchun Li, Jonathan A. Hickson, Dominic J. Ambrosi et al. · Molecular Cancer Therapeutics · 2018 · 43 citations

Generation of Dual-Variable-Domain Immunoglobulin Molecules for Dual-Specific Targeting

Jijie Gu, Tariq Ghayur · Methods in enzymology on CD-ROM/Methods in enzymology · 2011 · 41 citations

Immunoengineering, Immunology, Dual-variable-domain Immunoglobulin Molecules +4