Zuben E. Sauna

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

Medicine, Genetics, Molecular Genetics +15

Recent advances in (therapeutic protein) drug development

H. A. Daniel Lagassé, Aikaterini Alexaki, Vijaya L. Simhadri et al. · F1000Research · 2017 · 497 citations · Full text

Engineering, Biotechnology, Pharmaceutical Biotechnology +12

Prevalence of Pre-existing Antibodies to CRISPR-Associated Nuclease Cas9 in the USA Population

Vijaya L. Simhadri, Joseph R. McGill, Shane McMahon et al. · Molecular Therapy — Methods & Clinical Development · 2018 · 240 citations · Full text

Life Sciences, Biotechnology, Immunology +14

Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein

Zuben E. Sauna, Suresh V. Ambudkar · Proceedings of the National Academy of Sciences · 2000 · 216 citations

Life Sciences, Biochemistry, Pharmacology +17

Selective Toxicity of NSC73306 in MDR1-Positive Cells as a New Strategy to Circumvent Multidrug Resistance in Cancer

Joseph A. Ludwig, Gergely Szakács, Scott E. Martin et al. · Cancer Research · 2006 · 175 citations · Full text

Medicine, Oncology, Pharmacology +12