Polyphenols journey through blood-brain barrier towards neuronal protection

Inês Figueira, Gonçalo Garcia, R. C. Pimpão, +16

Scientific Reports

The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibition

Mónica Morais, Paulo AR Santos, António Mateus‐Pinheiro, +7

Journal of Psychopharmacology

Granule NeuronsStructural PlasticityHippocampal Adult NeurogenesisSocial SciencesAdult Neurogenesis +16

Blood–brain barrier transport and neuroprotective potential of blackberry-digested polyphenols: an in vitro study

Inês Figueira, Lucélia Tavares, Carolina Jardim, +15

European Journal of Nutrition

Blackberry-digested PolyphenolsPolyphenolicsFood Bioactive CompoundBiochemistryMedicine +7

Novel scalable 3D cell based model for in vitro neurotoxicity testing: Combining human differentiated neurospheres with gene expression and functional endpoints

Ana Paula Terrasso, Catarina Pinto, Margarida Serra, +6

Journal of Biotechnology

Vitro Neurotoxicity TestingNovel Scalable 3DMedicineCerebral OrganoidNeuroscience +6

Model‐Informed Drug Development: Steps Toward Harmonized Guidance

Scott Marshall, Malidi Ahamadi, Jenny Y. Chien, +21

Clinical Pharmacology & Therapeutics

Systems PharmacologyDrug SafetyPreclinical TherapeuticsDrug RepositioningTranslational Medicine +13

Human neuron-astrocyte 3D co-culture-based assay for evaluation of neuroprotective compounds

Ana Paula Terrasso, Ana Carina Silva, Augusto Filipe, +4

Journal of Pharmacological and Toxicological Methods

Neuro-oncologyNeurodegenerative DiseasesHuman Neuron-astrocyte 3DGliomaMedicine +9

Mycophenolate mofetil 500-mg tablet under fasting conditions: Single-dose, randomized-sequence, open-label, four-way replicate crossover, bioequivalence study in healthy subjects

Susana Almeida, Augusto Filipe, Rita Neves, +4

Clinical Therapeutics

Therapeutic Drug MonitoringHealthy SubjectsFour-way Replicate CrossoverPharmacologyPharmacotherapy +4

Results of a single-center, single-dose, randomized-sequence, open-label, two-way crossover bioequivalence study of two formulations of valsartan 160-mg tablets in healthy volunteers under fasting conditions

S. Cristina, Susana Almeida, Augusto Filipe, +2

Clinical Therapeutics

Pharmaceutical ScienceValsartan 160-Mg TabletsBioequivalenceMedicineHealthy Volunteers +3

Bioequivalence Study of Two Different Tablet Formulations of Carvedilol in Healthy Volunteers

Antonio Portolés, Augusto Filipe, Susana Almeida, +3

Arzneimittelforschung

Truncated AUCs in the Assessment of the Bioequivalence of Topiramate, a Long Half-life Drug

Susana Almeida, Augusto Filipe, Fethi Trabelsi, +1

Arzneimittelforschung