A.C.G. Hotze

Dinuclear Ruthenium(II) Triple‐Stranded Helicates: Luminescent Supramolecular Cylinders That Bind and Coil DNA and Exhibit Activity against Cancer Cell Lines

G.I. Pascu, A.C.G. Hotze, Carlos Sánchez-Cano et al. · Angewandte Chemie International Edition · 2007 · 195 citations

Supramolecular Assembly, Engineering, Molecular Biology +18

The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation

Marina Bacac, A.C.G. Hotze, Karlijn van der Schilden et al. · Journal of Inorganic Biochemistry · 2003 · 172 citations

Nmr Evaluation, Medicinal Chemistry, Dna Binding +8

Dinuclear Double‐Stranded Metallosupramolecular Ruthenium Complexes: Potential Anticancer Drugs

A.C.G. Hotze, Benson M. Kariuki, Michael J. Hannon · Angewandte Chemie International Edition · 2006 · 116 citations · Full text

Engineering, Metallosupramolecular Architecture, Red Ru +17

Structure-dependent in vitro cytotoxicity of the isomeric complexes [Ru(L)2Cl2] (L=o-tolylazopyridine and 4-methyl-2-phenylazopyridine) in comparison to [Ru(azpy)2Cl2]

A.C.G. Hotze, Dick de Vos, H. Kooijman et al. · JBIC Journal of Biological Inorganic Chemistry · 2004 · 88 citations

Biochemistry, Drug Resistance, Isomeric Complexes +6

Supramolecular Iron Cylinder with Unprecedented DNA Binding Is a Potent Cytostatic and Apoptotic Agent without Exhibiting Genotoxicity

A.C.G. Hotze, Nikolas J. Hodges, Rachel E. Hayden et al. · Chemistry & Biology · 2008 · 85 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +12