Hans den Dulk

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474

Annelot C. M. van Esbroeck, Antonius P. A. Janssen, Armand B. Cognetta et al. · Science · 2017 · 328 citations · Full text

Medicine, Neuroscience, Pharmacology +13

The Square-Planar Cytotoxic [Cu^II(pyrimol)Cl] Complex Acts as an Efficient DNA Cleaver without Reductant

Palanisamy Uma Maheswari, Sudeshna Roy, Hans den Dulk et al. · Journal of the American Chemical Society · 2005 · 229 citations · Full text

Medicine, Cancer Biology, Molecular Biology +10

Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition

Daisuke Ogasawara, Hui Deng, Andreu Viader et al. · Proceedings of the National Academy of Sciences · 2015 · 161 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes, in particular in redox and energy metabolism

Nan Li, Marianne Kraus, Nico J. Meeuwenoord et al. · Leukemia · 2016 · 154 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Folic Acid‐Modified Mesoporous Silica Nanoparticles for Cellular and Nuclear Targeted Drug Delivery

Fabiola Porta, Gerda E. M. Lamers, Jess Morrhayim et al. · Advanced Healthcare Materials · 2012 · 152 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17