Patrick T. Grogan

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

Gaspar J. Kitange, Brett L. Carlson, Mark A. Schroeder et al. · Neuro-Oncology · 2008 · 388 citations · Full text

Medicine, Cancer Biology, Oncology +17

Use of an Orthotopic Xenograft Model for Assessing the Effect of Epidermal Growth Factor Receptor Amplification on Glioblastoma Radiation Response

Jann N. Sarkaria, Brett L. Carlson, Mark A. Schroeder et al. · Clinical Cancer Research · 2006 · 279 citations

Medicine, Oncology, Radiation Oncology +16

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

Jann N. Sarkaria, Lin Yang, Patrick T. Grogan et al. · Molecular Cancer Therapeutics · 2007 · 203 citations

Medicine, Oncology, Pharmacology +16

Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model

Gaspar J. Kitange, Brett L. Carlson, Ann C. Mladek et al. · Journal of Neuro-Oncology · 2008 · 98 citations · Full text

Medicine, Molecular Biology, Oncology +16

Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines

Michelle J. Clarke, Evan A. Mulligan, Patrick T. Grogan et al. · Molecular Cancer Therapeutics · 2009 · 94 citations · Full text

Medicine, Oncology, Pharmacology +17