Ronghui Lin

Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

Ronghui Lin, Sigmond G. Johnson, Peter J. Connolly et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 126 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +7

1-Acyl-1<i>H</i>-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors:  Synthesis and Evaluation of Biological Activities

Ronghui Lin, Peter J. Connolly, Shenlin Huang et al. · Journal of Medicinal Chemistry · 2005 · 126 citations · Full text

Selective Cdk1, Medicinal Chemistry, Representative Compound 3B +13

The <i>In vitro</i> and <i>In vivo</i> Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases

Stuart L. Emanuel, Catherine A. Rugg, Robert H. Gruninger et al. · Cancer Research · 2005 · 122 citations · Full text

Dual Inhibitor, Cell Death, Total Cumulative Dose +22

Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors

Ronghui Lin, George Chiu, Yang Yu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 121 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +9

Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor

Shenlin Huang, Ronghui Lin, Yang Yu et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 108 citations · Full text

Medicinal Chemistry, Heterocyclic, Biochemistry +8