George Chiu

The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

Carlos Forray, Jonathan Bard, J. M. WETZEL et al. · Molecular Pharmacology · 1994 · 349 citations

Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors

Ronghui Lin, George Chiu, Yang Yu et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 121 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +9

Design and Synthesis of Novel α₁_a Adrenoceptor-Selective Antagonists. 1. Structure−Activity Relationship in Dihydropyrimidinones

Dhanapalan Nagarathnam, Shou Wu Miao, Bharat Lagu et al. · Journal of Medicinal Chemistry · 1999 · 112 citations · Full text

Organic Chemistry, Pharmacotherapy, Chemistry +16

Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor

Shenlin Huang, Ronghui Lin, Yang Yu et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 108 citations · Full text

Medicinal Chemistry, Heterocyclic, Biochemistry +8

Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents

Ronghui Lin, Peter J. Connolly, Yanhua Lü et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 80 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +7