Robert H. Gruninger

1-Acyl-1<i>H</i>-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors:  Synthesis and Evaluation of Biological Activities

Ronghui Lin, Peter J. Connolly, Shenlin Huang et al. · Journal of Medicinal Chemistry · 2005 · 128 citations · Full text

Medicine, Medicinal Chemistry, Oncology +13

The <i>In vitro</i> and <i>In vivo</i> Effects of JNJ-7706621: A Dual Inhibitor of Cyclin-Dependent Kinases and Aurora Kinases

Stuart L. Emanuel, Catherine A. Rugg, Robert H. Gruninger et al. · Cancer Research · 2005 · 125 citations · Full text

Medicine, Oncology, Pharmacology +13

Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors

Gee‐Hong Kuo, A. DeAngelis, Stuart L. Emanuel et al. · Journal of Medicinal Chemistry · 2005 · 92 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors

Guozhang Xu, M.C. Abad, Peter J. Connolly et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 89 citations · Full text

Medicine, Medicinal Chemistry, Oncology +11

Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents

Ronghui Lin, Peter J. Connolly, Yanhua Lü et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 80 citations · Full text

Medicine, Medicinal Chemistry, Oncology +9