Margaret Huggett

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against<i>Mycobacterium tuberculosis</i>

Yumi Park, A. Pacitto, Tracy Bayliss et al. · ACS Infectious Diseases · 2016 · 91 citations

Identification of Morpholino Thiophenes as Novel <i>Mycobacterium tuberculosis</i> Inhibitors, Targeting QcrB

Laura A. T. Cleghorn, Peter C. Ray, Joshua Odingo et al. · Journal of Medicinal Chemistry · 2018 · 56 citations · Full text

Drug Target, Bioorganic Chemistry, Antimicrobial Chemotherapy +20

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of <i>Mycobacterium tuberculosis</i> Growth

Peter C. Ray, Margaret Huggett, Penelope A. Turner et al. · ACS Omega · 2021 · 33 citations · Full text

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target

Caroline Wilson, Peter C. Ray, Fabio Zuccotto et al. · Journal of Medicinal Chemistry · 2021 · 33 citations · Full text

Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors

Peter C. Ray, Jane Wright, Julia Adam et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 29 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Natural Sciences +7