Searching for New Chemotherapies for Tropical Diseases: Ruthenium–Clotrimazole Complexes Display High in Vitro Activity against<i>Leishmania major</i>and<i>Trypanosoma cruzi</i>and Low Toxicity toward Normal Mammalian Cells

Alberto Martínez, Teresia A. Carreon, Eva Iniguez, +7

Journal of Medicinal Chemistry

Complex 8Antiparasitic AgentImmunologyNew Ruthenium ComplexesChemistry +19

Metal–drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells

Eva Iniguez, Antonio Sánchez, Miguel Vasquez, +5

JBIC Journal of Biological Inorganic Chemistry

Trypanosoma CruziMedicinal ChemistryBiochemistryAntiparasitic AgentMedicine +8

A prophylactic α-Gal-based glycovaccine effectively protects against murine acute Chagas disease

Susana Portillo, Brenda G. Zepeda, Eva Iniguez, +7

npj Vaccines

An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major

Eva Iniguez, Nathaniel S. Schocker, Krishanthi Subramaniam, +10

PLoS neglected tropical diseases

Aedes aegypti sialokinin facilitates mosquito blood feeding and modulates host immunity and vascular biology

Inés Martín-Martín, Paola Carolina Valenzuela Leon, Laura Amo, +10

Cell Reports

Microbial PathogensEntomologyImmunologyInnate Immune SystemSalivary Gland +15

Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis

Eva Iniguez, Armando Varela‐Ramírez, Alberto Martínez, +3

Acta Tropica

Ruthenium-clotrimazole ComplexAntiparasitic AgentMedicineParasitic ProtozoaMurine Model +8

Purification of Glycosylphosphatidylinositol-Anchored Mucins from Trypanosoma cruzi Trypomastigotes and Synthesis of α-Gal-Containing Neoglycoproteins: Application as Biomarkers for Reliable Diagnosis and Early Assessment of Chemotherapeutic Outcomes of Chagas Disease

Uriel Ortega‐Rodriguez, Susana Portillo, Roger A. Ashmus, +17

Methods in molecular biology

α-Gal-containing NeoglycoproteinsBiochemistryParasitic ProtozoaAfrican TrypanosomiasisBioanalysis +8

Heme Oxygenase-1 Induction by Blood-Feeding Arthropods Controls Skin Inflammation and Promotes Disease Tolerance

Thiago DeSouza‐Vieira, Eva Iniguez, Tiago D. Serafim, +17

Cell Reports

Leishmania genetic exchange is mediated by IgM natural antibodies

Tiago D. Serafim, Eva Iniguez, Ana Beatriz F. Barletta, +18

Nature

Autoimmune DiseaseParasitic ProtozoaMedicineLeishmania Genetic ExchangeImmunology +5

<i>In Vitro</i> and <i>In Vivo</i> Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors

Felipe Rodriguez, Sarah Finney John, Eva Iniguez, +6

Antimicrobial Agents and Chemotherapy