Paul J. Ciaccio

Modulation of Notch Processing by γ-Secretase Inhibitors Causes Intestinal Goblet Cell Metaplasia and Induction of Genes Known to Specify Gut Secretory Lineage Differentiation

Joseph Milano, Jenny McKay, Claude Dagenais et al. · Toxicological Sciences · 2004 · 557 citations

Genes Known, Gastroenterology, Pathology +17

Validation of an in vitro screen for phospholipidosis using a high-content biology platform

James K. Morelli, M. Buehrle, François Pognan et al. · Cell Biology and Toxicology · 2006 · 111 citations

Lipid Analysis, Lipid Preparation, Vitro Screen +10

Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

Paul J. Ciaccio, Kenneth D. Tew, Frank LaCreta · Biochemical Pharmacology · 1991 · 106 citations

Human Glutathione S-transferases, Enzymatic Conjugation, Bioorganic Chemistry +7

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced p<i>K</i>_a: Antibacterial Agents with an Improved Safety Profile

Folkert Reck, Richard A. Alm, Patrick Brassil et al. · Journal of Medicinal Chemistry · 2012 · 88 citations · Full text

Early Prediction of Polymyxin-Induced Nephrotoxicity With Next-Generation Urinary Kidney Injury Biomarkers

Natalie Keirstead, Matthew P. Wagoner, Patricia Bentley et al. · Toxicological Sciences · 2013 · 87 citations · Full text

Renal Pathology, Renal Inflammation, Pathology +18