Validation of an in vitro screen for phospholipidosis using a high-content biology platform

A Toxicogenomic Approach to Drug-Induced Phospholipidosis: Analysis of Its Induction Mechanism and Establishment of a Novel in Vitro Screening System

Hiroko Sawada · Toxicological Sciences · 2004 · 221 citations

Life Sciences, Molecular Biology, Toxicology +12

Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes, and blood leukocytes of patients with amiodarone pulmonary toxicity

Michael D. Dake, J. Mark Madison, Carolyn K. Montgomery et al. · The American Journal of Medicine · 1985 · 121 citations

Medicine, Cell Biology, Pathology +13

Studies on drug-induced lipidosis: subcellular localization of phospholipid and cholesterol in the liver of rats treated with chloroquine or 4,4'-bis (diethylaminoethoxy)alpha, beta-diethyldiphenylethane.

Yūji Matsuzawa, Karl Y. Hostetler · Journal of Lipid Research · 1980 · 107 citations · Full text

Life Sciences, Biochemistry, Pharmacology +12

Chloroquine-induced phospholipid fatty liver. Measurement of drug and lipid concentrations in rat liver lysosomes.

Karl Y. Hostetler, Mark J. Reasor, Paul J. Yazaki · Journal of Biological Chemistry · 1985 · 86 citations · Full text

Life Sciences, Pharmacology, Biochemical Pharmacology +10

Accumulation of weak bases in relation to intralysosomal pH in cultured human skin fibroblasts

M. Hollemans, Ronald Oude Elferink · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1981 · 82 citations

Life Sciences, Biochemistry, Cell Biology +5