Stepan Melnyk

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism

S. Jill James, Paul Cutler, Stepan Melnyk et al. · American Journal of Clinical Nutrition · 2004 · 934 citations

Increased Oxidative Stress, Biochemistry, Syndromic Autism +10

Increase in Plasma Homocysteine Associated with Parallel Increases in Plasma S-Adenosylhomocysteine and Lymphocyte DNA Hypomethylation

Ping Yi, Stepan Melnyk, Marta Pogribna et al. · Journal of Biological Chemistry · 2000 · 642 citations · Full text

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism

S. Jill James, Stepan Melnyk, Stefanie Jernigan et al. · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2006 · 598 citations · Full text

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

Shannon Rose, Stepan Melnyk, Oleksandra Pavliv et al. · Translational Psychiatry · 2012 · 473 citations · Full text

Autism Brain, Stress, Lipid Peroxidation +14

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome

S J James, Marta Pogribna, Igor P. Pogribny et al. · American Journal of Clinical Nutrition · 1999 · 450 citations · Full text

Down Syndrome, Mendelian Disorder, Genetic Disorder +8