Javier Pineda

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors

Wenyu Yu, Emma J. Chory, Amy K. Wernimont et al. · Nature Communications · 2012 · 286 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine

Hyun Jung Jun, Vicky A. Appleman, Hua-Jun Wu et al. · Nature Communications · 2018 · 51 citations · Full text

Medicine, Molecular Biology, Oncology +17

HIF activation causes synthetic lethality between the <i>VHL</i> tumor suppressor and the <i>EZH1</i> histone methyltransferase

Abhishek A. Chakraborty, Eijiro Nakamura, Jun Qi et al. · Science Translational Medicine · 2017 · 46 citations

Life Sciences, Cancer Biology, Molecular Biology +17

Site occupancy calibration of taxane pharmacology in live cells and tissues

Javier Pineda, Miles A. Miller, Yuyu Song et al. · Proceedings of the National Academy of Sciences · 2018 · 30 citations · Full text

Medicine, Oncology, Pharmacology +17

Replication Study: Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Anthony Essex, Javier Pineda, Grishma Acharya et al. · eLife · 2019 · 22 citations · Full text

Medicine, Cell Biology, Oncology +17