Rana Rais

Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion

Robert D. Leone, Liang Zhao, Judson M. Englert et al. · Science · 2019 · 1.1K citations

Immunology, Metabolic Remodeling, Immunotherapy +16

Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells

Min Hee Oh, Im‐Hong Sun, Liang Zhao et al. · Journal of Clinical Investigation · 2020 · 404 citations · Full text

Immunology, Immunoediting, Immunotherapy +17

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Amira Elgogary, Qingguo Xu, Brad Poore et al. · Proceedings of the National Academy of Sciences · 2016 · 223 citations · Full text

Design, Synthesis, and Pharmacological Evaluation of Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl Sulfide 3 (BPTES) Analogs as Glutaminase Inhibitors

Krupa H. Shukla, Dana Ferraris, Ajit G. Thomas et al. · Journal of Medicinal Chemistry · 2012 · 192 citations · Full text

Pharmaceutical Science, Glutaminase Inhibitors, Pharmacotherapy +16

Discovery of 6-Diazo-5-oxo-<scp>l</scp>-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma

Rana Rais, Andrej Jančařík, Lukáš Tenora et al. · Journal of Medicinal Chemistry · 2016 · 128 citations

Don Utilization, Pharmacotherapy, High-grade Gliomas +18