Andrew B. Benowitz

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Melissa B. Pappalardi, Kathryn Keenan, Mark Cockerill et al. · Nature Cancer · 2021 · 251 citations · Full text

Hematological Malignancy, Medicine, Acute Myeloid Leukemia +9

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Alina Mares, Afjal H. Miah, Ian E. Smith et al. · Communications Biology · 2020 · 209 citations · Full text

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Robert P. Law, João Nunes, Chun‐wa Chung et al. · Angewandte Chemie International Edition · 2021 · 112 citations

Fak Inhibitors, Molecular Biology, Degradation Reaction +17

Stereochemistry of the Core Structure of the Mycolactones

Andrew B. Benowitz, Steve Fidanze, Pamela L. C. Small et al. · Journal of the American Chemical Society · 2001 · 87 citations

Chemical Biology, Molecular Sciences, Bioorganic Chemistry +13

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

Chun‐wa Chung, Han Dai, Esther Fernández et al. · ACS Chemical Biology · 2020 · 86 citations