Afjal H. Miah

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +9

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Dennis L. Buckley, Kanak Raina, Nicole Darricarrère et al. · ACS Chemical Biology · 2015 · 476 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Alina Mares, Afjal H. Miah, Ian E. Smith et al. · Communications Biology · 2020 · 221 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach

Zuni I. Bassi, Martin C. Fillmore, Afjal H. Miah et al. · ACS Chemical Biology · 2018 · 178 citations

Life Sciences, Immunology, Molecular Biology +17

Optimization of a Series of RIPK2 PROTACs

Afjal H. Miah, Ian E. Smith, M.D. Rackham et al. · Journal of Medicinal Chemistry · 2021 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17