Afjal H. Miah

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson, Alina Mares, Ian E. Smith et al. · Nature Chemical Biology · 2015 · 1.3K citations · Full text

Biochemistry, Protein Assembly, Natural Sciences +2

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Dennis L. Buckley, Kanak Raina, Nicole Darricarrère et al. · ACS Chemical Biology · 2015 · 455 citations · Full text

Protein Assembly, Molecular Biology, Chemical Biology +18

Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2

Alina Mares, Afjal H. Miah, Ian E. Smith et al. · Communications Biology · 2020 · 209 citations · Full text

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach

Zuni I. Bassi, Martin C. Fillmore, Afjal H. Miah et al. · ACS Chemical Biology · 2018 · 173 citations

Inflammation, P300/cbp-associated Factor, Molecular Immunology +15

Optimization of a Series of RIPK2 PROTACs

Afjal H. Miah, Ian E. Smith, M.D. Rackham et al. · Journal of Medicinal Chemistry · 2021 · 65 citations · Full text