Benjamen D. Coats

Evidence that opioids may have toll-like receptor 4 and MD-2 effects

Mark R. Hutchinson, Yingning Zhang, Mitesh Shridhar et al. · Brain Behavior and Immunity · 2009 · 562 citations

Opioid Epidemic, Molecular Pharmacology, Health Sciences +12

Non‐stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll‐like receptor 4 (TLR4)

Mark R. Hutchinson, Yingning Zhang, Kimberley Brown et al. · European Journal of Neuroscience · 2008 · 389 citations · Full text

Pain Therapy, Pain Disorders, Pain Medicine +22

Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia

Mark R. Hutchinson, Benjamen D. Coats, Susannah S. Lewis et al. · Brain Behavior and Immunity · 2008 · 300 citations · Full text

Inflammation, Anti-inflammatory, Chronic Analgesia +10

Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)

Mark R. Hutchinson, Susannah S. Lewis, Benjamen D. Coats et al. · Brain Behavior and Immunity · 2008 · 297 citations · Full text

Acute Opioid Analgesia, Health Sciences, Medicine +14

Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences

Mark R. Hutchinson, Sara Lewis, Benjamen D. Coats et al. · Neuroscience · 2010 · 181 citations

Inflammation, Opioid Epidemic, Differentiation Factor-2 Activity +13