Ryota Shizu

PXR Functionally Interacts with NF-κB and AP-1 to Downregulate the Inflammation-Induced Expression of Chemokine CXCL2 in Mice

Maya Okamura, Ryota Shizu, Taiki Abe et al. · Cells · 2020 · 55 citations · Full text

Xenobiotic-Induced Hepatocyte Proliferation Associated with Constitutive Active/Androstane Receptor (CAR) or Peroxisome Proliferator-Activated Receptor α (PPARα) Is Enhanced by Pregnane X Receptor (PXR) Activation in Mice

Ryota Shizu, Satoshi Benoki, Yuki Numakura et al. · PLoS ONE · 2013 · 50 citations · Full text

X Receptor, Immunology, Cell Proliferation +17

Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation

Ryota Shizu, Makoto Osabe, L. Perera et al. · Molecular and Cellular Biology · 2017 · 39 citations · Full text

Molecular Biology, Constitutive Activity, Signaling Pathway +17

MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor

Ryota Shizu, Sawako Shindo, Takemi Yoshida et al. · PLoS ONE · 2012 · 35 citations · Full text

Engineering, Constitutive Androstane Receptor, Phenobarbital Activation +20

Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes

Taiki Abe, Yuto Amaike, Ryota Shizu et al. · Toxicological Sciences · 2018 · 33 citations

Transcriptional Regulation, Signaling Pathway, Cell Regulation +16