Makoto Osabe - Concepedia

Author

Makoto Osabe

University of Shizuoka ORCID

Also Known As

M Osabe, Makoto Osabe

Publications

578

Citations

H-Index

Concepts

All Affiliations

University of Shizuoka National Institutes of Health National Institute of Environmental Health Sciences

About

Makoto Osabe is an author at University of Shizuoka specializing in medicine, cell biology, and signal transduction.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	218
2	Cell Biology	4	4	173
3	Natural Sciences	2	2	97
4	Biochemistry	2	2	84
5	Health Sciences	1	1	45

Makoto Osabe

Publications

565

Citations

H-Index

Page 1

	Year	Citations
Dephosphorylation of Threonine 38 Is Required for Nuclear Translocation and Activation of Human Xenobiotic Receptor CAR (NR1I3) Shingo Mutoh, Makoto Osabe, Kaoru Inoue, Journal of Biological Chemistry	2009	134
Expression of Hepatic UDP-Glucuronosyltransferase 1A1 and 1A6 Correlated with Increased Expression of the Nuclear Constitutive Androstane Receptor and Peroxisome Proliferator-Activated Receptor α in Male Rats Fed a High-Fat and High-Sucrose Diet Makoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Drug Metabolism and Disposition	2007	90
Dietary Inulin Alleviates Hepatic Steatosis and Xenobiotics-Induced Liver Injury in Rats Fed a High-Fat and High-Sucrose Diet: Association with the Suppression of Hepatic Cytochrome P450 and Hepatocyte Nuclear Factor 4α Expression Junko Sugatani, Tadashi Wada, Makoto Osabe, Drug Metabolism and Disposition	2006	68
Active ERK1/2 Protein Interacts with the Phosphorylated Nuclear Constitutive Active/Androstane Receptor (CAR; NR1I3), Repressing Dephosphorylation and Sequestering CAR in the Cytoplasm Makoto Osabe, Masahiko Negishi Journal of Biological Chemistry ImmunologyMolecular BiologySignaling PathwayCell RegulationReceptor Tyrosine Kinase	2011	58
Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs: implication of defects in the UGT1A1 gene promoter Junko Sugatani, Kousuke Mizushima, Makoto Osabe, Naunyn-Schmiedeberg s Archives of Pharmacology Transcriptional RegulationGeneticsGene RegulationProximal Promoter MotifsUgt1a1 Gene Promoter	2008	57
Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high-sucrose (cafeteria) diet Junko Sugatani, Makoto Osabe, Tadashi Wada, European Journal of Nutrition NutritionMetabolic SyndromeBiochemistryMetabolic DiseaseDiabetes	2008	45
Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation Ryota Shizu, Makoto Osabe, L. Perera, Molecular and Cellular Biology Molecular BiologyConstitutive ActivitySignaling PathwayReceptor Tyrosine KinaseCar Homodimer	2017	39
Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression Junko Sugatani, Makoto Osabe, Masatoshi Kurosawa, Drug Metabolism and Disposition	2009	25
Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation Makoto Osabe, Junko Sugatani, Akiko Takemura, Biochemical and Biophysical Research Communications Developmental BiologySignal TransductionCell DivisionCell RegulationCell Interaction	2008	19
Up‐regulation of CAR expression through Elk‐1 in HepG2 and SW480 cells by serum starvation stress Makoto Osabe, Junko Sugatani, Akiko Takemura, FEBS Letters	2009	15

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