Melissa H. Costell

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

Kevin S. Thorneloe, Mui Cheung, Weike Bao et al. · Science Translational Medicine · 2012 · 328 citations

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

Reema K. Thalji, J. Jeffrey McAtee, Svetlana Belyanskaya et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 64 citations · Full text

Soluble Epoxide Hydrolase, Medicinal Chemistry, Biochemistry +5

Comparison of Soluble Guanylate Cyclase Stimulators and Activators in Models of Cardiovascular Disease Associated with Oxidative Stress

Melissa H. Costell, Nicolas Ancellin, Roberta E. Bernard et al. · Frontiers in Pharmacology · 2012 · 59 citations · Full text

Hypertension, Heart Failure, Cardiovascular Disease +14

Characterization of Small Molecule TRPC3 and TRPC6 agonist and Antagonists

Xiaoping Xu, Irina M. Lozinskaya, Melissa H. Costell et al. · Biophysical Journal · 2013 · 50 citations · Full text

Molecular Pharmacology, Molecular Physiology, Small Molecule Trpc3 +9

PPARδ Activation Normalizes Cardiac Substrate Metabolism and Reduces Right Ventricular Hypertrophy in Congestive Heart Failure

Beat M. Jucker, Christopher Doe, Christine G. Schnackenberg et al. · Journal of Cardiovascular Pharmacology · 2007 · 40 citations

Cardiac Muscle, Heart Failure, Cardiovascular Pharmacology +18