Melissa H. Costell - Concepedia

Author

Melissa H. Costell

GlaxoSmithKline (United States)

Also Known As

Costell, Melissa H., M.H. Costell, Melissa Costell, Melissa H Costell, Melissa H. Costell

Publications

700

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United States)South College Pathways Behavioral Services GlaxoSmithKline (United Kingdom)

About

Melissa H. Costell is an author at GlaxoSmithKline (United States) specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	252
2	Biochemistry	4	4	212
3	Health Sciences	2	2	79
4	Natural Sciences	2	2	114
5	Diabetes	1	1	39

Melissa H. Costell

Publications

686

Citations

H-Index

Page 1

	Year	Citations
An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure Kevin S. Thorneloe, Mui Cheung, Weike Bao, Science Translational Medicine	2012	328
Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase Reema K. Thalji, J. Jeffrey McAtee, Svetlana Belyanskaya, Bioorganic & Medicinal Chemistry Letters Soluble Epoxide HydrolaseMedicinal ChemistryBiochemistryNatural SciencesMedicine	2013	64
Comparison of Soluble Guanylate Cyclase Stimulators and Activators in Models of Cardiovascular Disease Associated with Oxidative Stress Melissa H. Costell, Nicolas Ancellin, Roberta E. Bernard, Frontiers in Pharmacology HypertensionHeart FailureCardiovascular DiseaseBiochemistryNitric Oxide	2012	59
Characterization of Small Molecule TRPC3 and TRPC6 agonist and Antagonists Xiaoping Xu, Irina M. Lozinskaya, Melissa H. Costell, Biophysical Journal Molecular PharmacologyMolecular PhysiologySmall Molecule Trpc3BiochemistryG Protein-coupled Receptor	2013	50
PPARδ Activation Normalizes Cardiac Substrate Metabolism and Reduces Right Ventricular Hypertrophy in Congestive Heart Failure Beat M. Jucker, Christopher Doe, Christine G. Schnackenberg, Journal of Cardiovascular Pharmacology Cardiac MuscleHeart FailureCardiovascular PharmacologyPharmacotherapyCardiovascular Function	2007	40
Chronic Inhibition of 11<i>β</i>-Hydroxysteroid Dehydrogenase Type 1 Activity Decreases Hypertension, Insulin Resistance, and Hypertriglyceridemia in Metabolic Syndrome Christine G. Schnackenberg, Melissa H. Costell, Daniel J. Krosky, BioMed Research International HypertensionMetabolic DisorderCardiometabolic RiskGlucocorticoidObesity	2013	39
Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model Joseph E. Pero, Jay M. Matthews, David J. Behm, Journal of Medicinal Chemistry	2018	34
Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4) Edward J. Brnardic, Guosen Ye, Carl Brooks, Journal of Medicinal Chemistry	2018	27
Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4) Carl Brooks, Linda S. Barton, David J. Behm, Journal of Medicinal Chemistry	2019	23
Rosiglitazone Protects against Ischemia/Reperfusion-Induced Leukocyte Adhesion in the Zucker Diabetic Fatty Rat Douglas G. Johns, Zhaohui Ao, Marianne Eybye, Journal of Pharmacology and Experimental Therapeutics	2005	22

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