Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

Susanne Steggerda, Mark K. Bennett, Jason Chen, +18

Journal for ImmunoTherapy of Cancer

Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer

Milica Momcilovic, Sean T. Bailey, Jason T. Lee, +23

Cell Reports

Fully Human Bcma Targeted Chimeric Antigen Receptor T Cells Administered in a Defined Composition Demonstrate Potency at Low Doses in Advanced Stage High Risk Multiple Myeloma

Damian J. Green, Margot J. Pont, Blythe Sather, +16

Blood

Enhanced long‐term potentiation and impaired learning in phosphodiesterase 4D‐knockout (<i>PDE4D</i>^−/−) mice

Kris Rutten, Dinah Misner, Melissa Works, +4

European Journal of Neuroscience

Inhibition of TYK2 and JAK1 Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis by Inhibiting IL-22 and the IL-23/IL-17 Axis

Melissa Works, F Yin, Catherine Yin, +9

The Journal of Immunology

Sar-20347 DoseImmunologyImmune RegulationIl-23/il-17 AxisDermatology +15

Anti–B-cell Maturation Antigen Chimeric Antigen Receptor T cell Function against Multiple Myeloma Is Enhanced in the Presence of Lenalidomide

Melissa Works, Neha Soni, Collin Hauskins, +15

Molecular Cancer Therapeutics

Efficacy and Safety of Fully Human Bcma CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase Bcma Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot J. Pont, Blythe Sather, +15

Blood

Enhanced long-term depression and impaired reversal learning in phosphodiesterase 4B-knockout (PDE4B−/−) mice

Kris Rutten, Tanya L. Wallace, Melissa Works, +5

Neuropharmacology

Synaptic PlasticityMolecular NeurosciencePsychiatryLong-term DepressionNeurotransmitter +7

Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum

Jie Li, Terence Duarte, Arif Kocabas, +3

Molecular and Cellular Neuroscience

Differential Netrin-1 ExpressionCellular NeuroscienceNeuroanatomyNeurotransmitterSocial Sciences +11

Response to Bcma CAR-T Cells Correlates with Pretreatment Target Antigen Density and Is Improved By Small Molecule Inhibition of Gamma Secretase

Damian J. Green, Margot J. Pont, Andrew J. Cowan, +11

Blood