Margot J. Pont

γ-Secretase inhibition increases efficacy of BCMA-specific chimeric antigen receptor T cells in multiple myeloma

Margot J. Pont, Tyler Hill, Gabriel O. Cole et al. · Blood · 2019 · 324 citations · Full text

Life Sciences, Immunology, Oncology +14

Fully Human Bcma Targeted Chimeric Antigen Receptor T Cells Administered in a Defined Composition Demonstrate Potency at Low Doses in Advanced Stage High Risk Multiple Myeloma

Damian J. Green, Margot J. Pont, Blythe Sather et al. · Blood · 2018 · 129 citations

Life Sciences, Immunology, Oncology +14

γ-Secretase inhibitor in combination with BCMA chimeric antigen receptor T-cell immunotherapy for individuals with relapsed or refractory multiple myeloma: a phase 1, first-in-human trial

Andrew J. Cowan, Margot J. Pont, Blythe Sather et al. · The Lancet Oncology · 2023 · 98 citations · Full text

Medicine, Immunology, Oncology +17

Efficacy and Safety of Fully Human Bcma CAR T Cells in Combination with a Gamma Secretase Inhibitor to Increase Bcma Surface Expression in Patients with Relapsed or Refractory Multiple Myeloma

Andrew J. Cowan, Margot J. Pont, Blythe Sather et al. · Blood · 2019 · 64 citations

Life Sciences, Immunology, Oncology +16

Pathogen-Specific Humoral Immunity and Infections in B Cell Maturation Antigen-Directed Chimeric Antigen Receptor T Cell Therapy Recipients with Multiple Myeloma

Srirama Josyula, Margot J. Pont, Sayan Dasgupta et al. · Transplantation and Cellular Therapy · 2022 · 41 citations · Full text

Life Sciences, Hematology, Immunology +17