Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

Matej Orešič, Satu Simell, Marko Sysi‐Aho, +19

The Journal of Experimental Medicine

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial

Kirsti Näntö‐Salonen, Antti Kupila, Satu Simell, +16

The Lancet

Type 1Diabetes ManagementAutoimmune DiseaseNasal InsulinInsulin Management +7

Predictive Characteristics of Diabetes-Associated Autoantibodies Among Children With HLA-Conferred Disease Susceptibility in the General Population

Heli Siljander, Satu Simell, Anne Hekkala, +7

Diabetes

Ketoacidosis at Diagnosis of Type 1 Diabetes in Children in Northern Finland

Anne Hekkala, Mikael Knip, Riitta Veijola

Diabetes Care

Fate of Five Celiac Disease-Associated Antibodies During Normal Diet in Genetically At-Risk Children Observed from Birth in a Natural History Study

Satu Simell, Sanna Hoppu, Anne Hekkala, +11

The American Journal of Gastroenterology

Age-Related Differences in the Frequency of Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents

Anne Hekkala, Antti Reunanen, Matti Koski, +2

Diabetes Care

Natural history of transglutaminase autoantibodies and mucosal changes in children carrying HLA-conferred celiac disease susceptibility

Satu Simell, Antti Kupila, Sanna Hoppu, +9

Scandinavian Journal of Gastroenterology

Ketoacidosis at diagnosis of type 1 diabetes: Effect of prospective studies with newborn genetic screening and follow up of risk children

Anne Hekkala, Jorma Ilonen, Jorma Toppari, +2

Pediatric Diabetes

Type 1Dka RiskNewborn ScreeningDiabetes EpidemiologyPediatric Epidemiology +11

RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis

Artem Kalinichenko, Giovanna Perinetti Casoni, Luca Trotta, +20

Blood

Family history of diabetes and distribution of class II HLA genotypes in children with newly diagnosed type 1 diabetes: effect on diabetic ketoacidosis

Anne Hekkala, Jorma Ilonen, Mikael Knip, +1

European Journal of Endocrinology