Colm O’Dushlaine

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, Jian Yang, Hilary K. Finucane et al. · The American Journal of Human Genetics · 2015 · 1.5K citations · Full text

Linkage Disequilibrium, Engineering, Polygenic Risk +4

Computationally efficient whole-genome regression for quantitative and binary traits

Joelle Mbatchou, Leland Barnard, Joshua Backman et al. · Nature Genetics · 2021 · 1.4K citations · Full text

Genome-wide Association Study, Quantitative Genetics, Genotype-phenotype Association +10

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology

Jonas B. Nielsen, Rósa B. Þórólfsdóttir, Lars G. Fritsche et al. · Nature Genetics · 2018 · 900 citations

Cardiomyopathy, Functional Genomics, Engineering +12

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

Frederick E. Dewey, Viktoria Gusarova, Richard L. Dunbar et al. · New England Journal of Medicine · 2017 · 836 citations · Full text

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Douglas M. Ruderfer, Stephan Ripke, Andrew McQuillin et al. · Cell · 2018 · 797 citations · Full text

Psychiatry, Psychotic Disorder, Genetics +7