Regression Shrinkage and Selection Via the Lasso

Robert Tibshirani

Journal of the Royal Statistical Society Series B (Statistical Methodology)

EngineeringHigh-dimensional MethodRobust ModelingEstimation StatisticFeature Selection +12

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton, David Clayton, Lon R. Cardon, +32

Nature

Genome-wide Association StudyDisease SusceptibilityDisease EtiologyGlobal HealthGenetic Epidemiology +7

Biological insights from 108 schizophrenia-associated genetic loci

Kai-How Farh, Brendan Bulik‐Sullivan

Nature

PsychiatryBiological InsightsGeneticsPsychiatric GeneticsSchizophrenia +3

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Brendan Bulik‐Sullivan, Po‐Ru Loh, Hilary K. Finucane, +5

Nature Genetics

Genome-wide Association StudyGenetic DeterminantGenotype-phenotype AssociationGeneticsPolygenic Risk +7

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Edward M. Scolnick

Nature

PsychiatryRisk PredictionPsychotic DisorderGeneticsPolygenic Risk +11

XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance.

R. A. Fisher

Transactions of the Royal Society of Edinburgh

Standard DeviationsPhenotypic VariationKin RecognitionGeneticsHuman Variation +24

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Sven Bergmann, Gert‐Jan B. van Ommen

Nature Genetics

ObesityGenome-wide Association StudyBody CompositionBody SizeBody Mass Index +9

Partitioning heritability by functional annotation using genome-wide association summary statistics

Hilary K. Finucane, Brendan Bulik‐Sullivan, Alexander Gusev, +18

Nature Genetics

Genome-wide Association StudyGenetic AnalysisGenotype-phenotype AssociationGeneticsLinkage Analysis +10

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer, Sabine Cepok, Jeremy Hobart, +1

Nature

ImmunogeneticsDisease SusceptibilityAutoimmune DiseaseAdaptive Immune SystemImmune Cell Development +13

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Hana Lango Allen, Karol Estrada, Guillaume Lettre, +287

Nature

Genome-wide Association StudyGenetic AnalysisAllelic VariantQuantitative GeneticsGenotype-phenotype Association +11