Ikuo Murakami

Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

Shashi Kumar Gupta, Masao Hirota, Sheela Waugh et al. · Journal of Biological Chemistry · 2014 · 149 citations · Full text

Inflammation, Cytokine, Immunology +8

Allergic Airway Inflammation by Nasal Inoculation of Particulate Matter (PM2.5) in NC/Nga Mice

Keiki Ogino, Ran Zhang, Hidekazu Takahashi et al. · PLoS ONE · 2014 · 95 citations · Full text

Acute Lung Injury, Environmental Allergy, Inflammatory Lung Disease +21

Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys

Masao Hirota, Ikuo Murakami, Yuichi Ishikawa et al. · Nucleic Acid Therapeutics · 2015 · 38 citations · Full text

Immunology, Inflammatory Arthritis, Inflammation +18

L-Arginine administration attenuates airway inflammation by altering L-arginine metabolism in an NC/Nga mouse model of asthma

Ran Zhang, Masayuki Kubo, Ikuo Murakami et al. · Journal of Clinical Biochemistry and Nutrition · 2015 · 22 citations · Full text

Asthma, Acute Lung Injury, Inflammatory Lung Disease +17

Evaluation of serum arginase I as an oxidative stress biomarker in a healthy Japanese population using a newly established ELISA

Keiki Ogino, Ikuo Murakami, Da-Hong Wang et al. · Clinical Biochemistry · 2013 · 15 citations

Allergy, Bioanalysis, Pathogenesis +10