Darren Chan

A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models

Bettina van Lengerich, Lihong Zhan, Dan Xia et al. · Nature Neuroscience · 2023 · 213 citations · Full text

The pore density in the inner wall endothelium of Schlemm's canal of glaucomatous eyes.

Mark Johnson, Darren Chan, A. Thomas Read et al. · PubMed · 2002 · 130 citations

Biomechanics of Schlemm's Canal Endothelial Cells: Influence on F-Actin Architecture

C. Ross Ethier, A. Thomas Read, Darren Chan · Biophysical Journal · 2004 · 102 citations · Full text

Mechanobiology, Engineering, Biomechanics +13

The AMPK-PGC-1α signaling axis regulates the astrocyte glutathione system to protect against oxidative and metabolic injury

Xiaoxin Guo, Qi Jiang, Alessandra Tuccitto et al. · Neurobiology of Disease · 2018 · 86 citations · Full text

Redox Signaling, Signal Transduction, Physiology +10

Effects of Latrunculin-B on Outflow Facility and Trabecular Meshwork Structure in Human Eyes

C. Ross Ethier, A. Thomas Read, Darren Chan · Investigative Ophthalmology & Visual Science · 2006 · 84 citations