Mei‐Kuang Chen

PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression

Shiping Jiao, Weiya Xia, Hirohito Yamaguchi et al. · Clinical Cancer Research · 2017 · 943 citations · Full text

Blocking c-Met–mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors

Yi Du, Hirohito Yamaguchi, Yongkun Wei et al. · Nature Medicine · 2016 · 240 citations · Full text

Tumor Biology, Medicine, Pharmacology +7

Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing.

Linlin Sun, Ri‐Yao Yang, Chia-Wei Li et al. · PubMed · 2018 · 124 citations · Full text

Immunology, Sensitizes Tumor Cells, Cell Death +16

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death

Jerry H. Houl, Zu Ye, Chris A. Brosey et al. · Nature Communications · 2019 · 122 citations · Full text

Definition of PKC-α, CDK6, and MET as Therapeutic Targets in Triple-Negative Breast Cancer

Yi‐Hsin Elsa Hsu, Jun Yao, Li-Chuan Chan et al. · Cancer Research · 2014 · 83 citations · Full text