Mei‐Kuang Chen - Concepedia

Author

Mei‐Kuang Chen

The University of Texas MD Anderson Cancer Center ORCID

Also Known As

Mei Kuang Chen, Mei-Kuang Chen, MeiKuang Chen, Meikuang Chen, Mei Kuang Chen, Mei‐Kuang Chen

Publications

2.1K

Citations

H-Index

Concepts

All Affiliations

The University of Texas MD Anderson Cancer Center China Medical University Asia University The University of Texas Health Science Center at Houston Mackay Memorial Hospital

About

Mei‐Kuang Chen is an author at The University of Texas MD Anderson Cancer Center specializing in medicine, tumor biology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	445
2	Cell Biology	5	5	416
3	Immunology	3	3	167
4	Pharmacology	3	3	287
5	Cancer Cell Biology	3	3	274

Mei‐Kuang Chen

Publications

1.9K

Citations

H-Index

Page 1

	Year	Citations
PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression Shiping Jiao, Weiya Xia, Hirohito Yamaguchi, Clinical Cancer Research	2017	943
Blocking c-Met–mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors Yi Du, Hirohito Yamaguchi, Yongkun Wei, Nature Medicine Tumor BiologyMedicinePharmacologyCancer Cell BiologyParp Inhibitors	2016	240
Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing. Linlin Sun, Ri‐Yao Yang, Chia-Wei Li, PubMed ImmunologySensitizes Tumor CellsCell DeathImmunotherapyPd-l1 Levels	2018	124
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death Jerry H. Houl, Zu Ye, Chris A. Brosey, Nature Communications	2019	122
Definition of PKC-α, CDK6, and MET as Therapeutic Targets in Triple-Negative Breast Cancer Yi‐Hsin Elsa Hsu, Jun Yao, Li-Chuan Chan, Cancer Research	2014	83
EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma Qiongzhu Dong, Yi Du, Hui Li, Cancer Research	2018	66
Blocking c-Met and EGFR reverses acquired resistance of PARP inhibitors in triple-negative breast cancer. Yu‐Yi Chu, Clinton Yam, Mei‐Kuang Chen, PubMed	2020	44
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in <i>BRCA1</i> -Deficient Cancers Guang Lei, Chao Mao, Amber D. Horbath, Cancer Discovery	2024	38
Targeting the ALK–CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex Yu‐Yi Chu, Mei‐Kuang Chen, Yongkun Wei, Nature Cancer	2022	36
Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells. Ye Han, Mei‐Kuang Chen, Hung-Ling Wang, PubMed	2019	33

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