Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Jong‐Ho Cha, Wenhao Yang, Weiya Xia, +25

Molecular Cell

MedicineEndoplasmic-reticulum-associated DegradationApoptosisImmunologyTumor Immunity +2

Precambrian Sponges with Cellular Structures

Chia-Wei Li, Junyuan Chen, Tzu-En Hua

Science

An early Cambrian craniate-like chordate

Junyuan Chen, Diying Huang, Chia-Wei Li

Nature

GeologyPrecambrian GeologyBiologyCraton

Small Bilaterian Fossils from 40 to 55 Million Years Before the Cambrian

Junyuan Chen, David J. Bottjer, Paola Oliveri, +6

Science

BiologySmall Bilaterian FossilsMyriapodaMorphological EvidencePhosphatized Specimens +13

Precambrian animal diversity: Putative phosphatized embryos from the Doushantuo Formation of China

Junyuan Chen, Paola Oliveri, Chia-Wei Li, +5

Proceedings of the National Academy of Sciences

BiologySynapsidaDevelopmental BiologyLiving FossilDoushantuo Formation +13

Localization of GRP78 to mitochondria under the unfolded protein response

Fang‐Chun Sun, Shou Wei, Chia-Wei Li, +3

Biochemical Journal

Protein FunctionMitochondrial BiogenesisBiochemistryMitochondrial FunctionProtein Folding +12

Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity

Linlin Sun, Chia-Wei Li, Ezra M. Chung, +17

Cancer Research

Cancer ImmunosurveillanceLigand Pd-l1Pd-l1/pd-1 BindingPd-1 GlycosylationT-regulatory Cell +10

Precambrian Animal Life: Probable Developmental and Adult Cnidarian Forms from Southwest China

Junyuan Chen, Paola Oliveri, Feng Gao, +4

Developmental Biology

BiologyLiving FossilNatural SciencesPrecambrian GeologyEvolutionary Biology +5

SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway

Chenhao Zhou, Chunxiao Liu, Wenjie Liu, +15

Theranostics

Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing.

Linlin Sun, Ri‐Yao Yang, Chia-Wei Li, +8

PubMed

ImmunologySensitizes Tumor CellsCell DeathImmunotherapyPd-l1 Levels +14