Ralph Tiedt

A Gain-of-Function Mutation of <i>JAK2</i> in Myeloproliferative Disorders

Róbert Královics, Francesco Passamonti, Andreas Buser et al. · New England Journal of Medicine · 2005 · 3.5K citations · Full text

Life Sciences, Genetics, Hematology +15

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 701 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Polyclonal Secondary <i>FGFR2</i> Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion–Positive Cholangiocarcinoma

Lipika Goyal, Supriya K. Saha, Leah Y. Liu et al. · Cancer Discovery · 2016 · 545 citations · Full text

Medicine, Molecular Biology, Oncology +17

Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice

Ralph Tiedt, Hui Hao-Shen, Marta Sobas et al. · Blood · 2007 · 434 citations · Full text

Veterinary Medicine, Genetics, Molecular Genetics +12

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

Ralph Tiedt, Tibor Schomber, Hui Hao-Shen et al. · Blood · 2006 · 418 citations

Life Sciences, Cell Biology, Genetics +14