Darren H. Freed

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients

Evangelos D. Michelakis, Vikram Gurtu, Linda Webster et al. · Science Translational Medicine · 2017 · 298 citations

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

Jon‐Jon Santiago, Aran L. Dangerfield, Sunil G. Rattan et al. · Developmental Dynamics · 2010 · 265 citations

Survival after pulmonary thromboendarterectomy: Effect of residual pulmonary hypertension

Darren H. Freed, Bruce Thomson, Marius Berman et al. · Journal of Thoracic and Cardiovascular Surgery · 2010 · 255 citations · Full text

Pulmonary Embolism, Hypertension, Thrombosis +9

Functional assessment and transplantation of the donor heart after circulatory death

Simon Messer, Richard G. Axell, Simon Colah et al. · The Journal of Heart and Lung Transplantation · 2016 · 245 citations

Functional Assessment, Heart Failure, Transplantation +9

Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

Saeid Ghavami, R H Cunnington, Shivani Gupta et al. · Cell Death and Disease · 2015 · 208 citations · Full text