Darren H. Freed

Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients

Evangelos D. Michelakis, Vikram Gurtu, Linda Webster et al. · Science Translational Medicine · 2017 · 311 citations

Medicine, Cardiology, Pharmacology +7

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

Jon‐Jon Santiago, Aran L. Dangerfield, Sunil G. Rattan et al. · Developmental Dynamics · 2010 · 268 citations

Life Sciences, Cardiology, Cell Biology +11

Survival after pulmonary thromboendarterectomy: Effect of residual pulmonary hypertension

Darren H. Freed, Bruce Thomson, Marius Berman et al. · Journal of Thoracic and Cardiovascular Surgery · 2010 · 256 citations · Full text

Medicine, Hematology, Surgery +9

Functional assessment and transplantation of the donor heart after circulatory death

Simon Messer, Richard G. Axell, Simon Colah et al. · The Journal of Heart and Lung Transplantation · 2016 · 256 citations

Medicine, Cardiology, Surgery +16

Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

Saeid Ghavami, R H Cunnington, Shivani Gupta et al. · Cell Death and Disease · 2015 · 214 citations · Full text

Life Sciences, Cardiology, Cell Biology +14