UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

Helena M. Feldmann, Valeria Golozoubova, Barbara Cannon, +1

Cell Metabolism

ObesityMetabolic SyndromeThermal StressEnergy MetabolismEnergy Homeostasis +9

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

Nataša Petrovič, Tomas B. Waldén, Irina G. Shabalina, +3

Journal of Biological Chemistry

Metabolic RemodelingCellular PhysiologyThermogenically CompetentMetabolic SyndromeBrown Adipocytes +15

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages

James A. Timmons, Kristian Wennmalm, Ola Larsson, +9

Proceedings of the National Academy of Sciences

Skeletal Muscle CellsMetabolic DisorderGene Regulatory NetworkCellular PhysiologyInsulin Signaling +15

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

Maria Cristina Zingaretti, Francesca Crosta, Alessandra Vitali, +5

The FASEB Journal

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

Irina G. Shabalina, Nataša Petrovič, Jasper M. A. de Jong, +3

Cell Reports

Metabolic SyndromeEnergy MetabolismUcp1 KnockoutFat-burning PropertiesMitochondrial Function +11

Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues

Tomas B. Waldén, Ida R. Hansen, James A. Timmons, +2

American Journal of Physiology-Endocrinology and Metabolism

GeneticsGene Expression PatternMolecular BiologyGene CharacterizationMolecular Genetics +21

BMP8B Increases Brown Adipose Tissue Thermogenesis through Both Central and Peripheral Actions

Andrew J. Whittle, Stefania Carobbio, Luís Martins, +14

Cell

A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

Naja Zenius Jespersen, Therese Juhlin Larsen, Lone Peijs, +10

Cell Metabolism

ObesityMetabolic SyndromeDevelopmental BiologyBody CompositionHealth Sciences +10

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

Valeria Golozoubova, Esa Hohtola, A. Matthias, +3

The FASEB Journal

Molecular BiologyCellular PhysiologyProtein FoldingMetabolismSuccessive Acclimation +15

The Browning of White Adipose Tissue: Some Burning Issues

Jan Nedergaard, Barbara Cannon

Cell Metabolism

ObesityMetabolic SyndromeBody CompositionMetabolic DisorderPhysiology +8