UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

A role for brown adipose tissue in diet-induced thermogenesis

Nancy J. Rothwell, Michael J. Stock · Nature · 1979 · 1.6K citations

Life Sciences, Biochemistry, Physiology +14

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Sven Enerbäck, Anders Jacobsson, Elizabeth M. Simpson et al. · Nature · 1997 · 1.4K citations

Life Sciences, Biochemistry, Physiology +12

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

Valeria Golozoubova, Esa Hohtola, A. Matthias et al. · The FASEB Journal · 2001 · 510 citations · Full text

Life Sciences, Molecular Biology, Physiology +17

Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity

Camille C. Caldeira da Silva, Fernanda M. Cerqueira, Lívea Fujita Barbosa et al. · Aging Cell · 2008 · 339 citations · Full text

Life Sciences, Nutritional Sciences, Physiology +17

Reduced thermogenesis in obesity

Roland Jung, P. S. Shetty, W. P. T. James et al. · Nature · 1979 · 296 citations

Life Sciences, Biology, Physiology +10