Igor Bruzual

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance

Laura A. Kirkman, Wenhu Zhan, Joseph E. Visone et al. · Proceedings of the National Academy of Sciences · 2018 · 97 citations · Full text

Development of an Orally Available and Central Nervous System (CNS) Penetrant <i>Toxoplasma gondii</i> Calcium-Dependent Protein Kinase 1 (<i>Tg</i>CDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of <i>Toxoplasmosis</i>

Rama Subba Rao Vidadala, Kasey Rivas, Kayode K. Ojo et al. · Journal of Medicinal Chemistry · 2016 · 96 citations · Full text

Immunology, Pathology, Cell Death +17

Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone

Lauren Lawres, Aprajita Garg, Vidya P. Kumar et al. · The Journal of Experimental Medicine · 2016 · 89 citations · Full text

Genetic Evidence for Cytochrome <i>b</i> Q _i Site Inhibition by 4(1 <i>H</i> )-Quinolone-3-Diarylethers and Antimycin in Toxoplasma gondii

P. Holland Alday, Igor Bruzual, Aaron Nilsen et al. · Antimicrobial Agents and Chemotherapy · 2016 · 57 citations · Full text

Biofilm formation by fluconazole-resistant Candida albicans strains is inhibited by fluconazole

Igor Bruzual, Perry J. Riggle, Susan Hadley et al. · Journal of Antimicrobial Chemotherapy · 2007 · 50 citations · Full text