Matthew J. Winton

Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation

Matthew J. Winton, Lionel M. Igaz, Margaret Wong et al. · Journal of Biological Chemistry · 2008 · 656 citations · Full text

Molecular Biology, Degenerative Pathology, Genome Instability +16

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

Lionel M. Igaz, Linda K. Kwong, Edward B. Lee et al. · Journal of Clinical Investigation · 2011 · 440 citations · Full text

Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system

Catherine Dubreuil, Matthew J. Winton, Lisa McKerracher · The Journal of Cell Biology · 2003 · 395 citations · Full text

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

Lionel M. Igaz, Linda K. Kwong, Alice Chen‐Plotkin et al. · Journal of Biological Chemistry · 2009 · 366 citations · Full text

Protein Function, Signal Transduction, Als Brain +15

TDP-43 Mediates Degeneration in a Novel<i>Drosophila</i>Model of Disease Caused by Mutations in VCP/p97

Gillian P. Ritson, Sara K. Custer, Brian D. Freibaum et al. · Journal of Neuroscience · 2010 · 264 citations · Full text