Lionel M. Igaz

Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation

Matthew J. Winton, Lionel M. Igaz, Margaret Wong et al. · Journal of Biological Chemistry · 2008 · 656 citations · Full text

Molecular Biology, Degenerative Pathology, Genome Instability +16

Persistence of Long-Term Memory Storage Requires a Late Protein Synthesis- and BDNF- Dependent Phase in the Hippocampus

Pedro Bekinschtein, Martı́n Cammarota, Lionel M. Igaz et al. · Neuron · 2007 · 625 citations · Full text

Bdnf- Dependent Phase, Storage (Memory), Cognitive Science +10

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

Lionel M. Igaz, Linda K. Kwong, Edward B. Lee et al. · Journal of Clinical Investigation · 2011 · 440 citations · Full text

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

Lionel M. Igaz, Linda K. Kwong, Alice Chen‐Plotkin et al. · Journal of Biological Chemistry · 2009 · 366 citations · Full text

Protein Function, Signal Transduction, Als Brain +15

Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Lionel M. Igaz, Linda K. Kwong, Yan Xu et al. · American Journal Of Pathology · 2008 · 331 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Biology +8