Robert Westwood

2-(Oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors

W. R. TULLY, Carol R. Gardner, R. J. Gillespie et al. · Journal of Medicinal Chemistry · 1991 · 274 citations

Dihydroorotate Dehydrogenase Is a High Affinity Binding Protein for A77 1726 and Mediator of a Range of Biological Effects of the Immunomodulatory Compound

Richard A. Williamson, Christopher Yea, P.A. Robson et al. · Journal of Biological Chemistry · 1995 · 196 citations · Full text

Purification of human dihydro-orotate dehydrogenase and its inhibition by A77 1726, the active metabolite of leflunomide

Jean‐Michel Bruneau, Christopher Yea, Sylviane Spinella-Jaegle et al. · Biochemical Journal · 1998 · 146 citations · Full text

Synthesis, Structure−Activity Relationships, and Pharmacokinetic Properties of Dihydroorotate Dehydrogenase Inhibitors:  2-Cyano-3-cyclopropyl-3-hydroxy- <i>N</i>-[3‘-methyl-4‘-(trifluoromethyl)phenyl]propenamide and Related Compounds

Elizabeth Kuo, P. Hambleton, David P. Kay et al. · Journal of Medicinal Chemistry · 1996 · 90 citations · Full text

Pharmaceutical Science, Pyrimidine Biosynthesis, Pharmacotherapy +19

(Imidazo[1,2-a]pyrimidin-2-yl)phenylmethanones and related compounds as potential nonsedative anxiolytics

S. Clements-Jewery, G. W. DANSWAN, Colin Gardner et al. · Journal of Medicinal Chemistry · 1988 · 79 citations