Cody Krivacic

Computational design of a modular protein sense-response system

Anum Glasgow, Yao-Ming Huang, Daniel J. Mandell et al. · Science · 2019 · 132 citations · Full text

Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (<i>R</i>)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2<i>H</i>)-one (PF-06821497)

Pei‐Pei Kung, Patrick Bingham, Alexei Brooun et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text

Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2 <i>H</i> )-ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors

Pei‐Pei Kung, Eugene Rui, Simon Bergqvist et al. · Journal of Medicinal Chemistry · 2016 · 66 citations · Full text

SAH derived potent and selective EZH2 inhibitors

Pei‐Pei Kung, Buwen Huang, Luke R. Zehnder et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 21 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +6

Computational design of a modular protein sense/response system

Anum Glasgow, Yao-Ming Huang, Daniel J. Mandell et al. · 2019 · 17 citations · Full text