Francis Hubler

4-((<i>R</i>)-2-{[6-((<i>S</i>)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y₁₂ Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

Eva Caroff, Francis Hubler, Emmanuel A. Meyer et al. · Journal of Medicinal Chemistry · 2015 · 50 citations

Disease-relevant Platelet Aggregation, Pharmacotherapy, Experimental Pharmacology +20

Cyclosporin A prodrugs: design, synthesis and biophysical properties

Arnaud Hamel, Francis Hubler, A. Carrupt et al. · Journal of Peptide Research · 2004 · 40 citations

Synthetic routes to NEtXaa4-cyclosporin A derivatives as potential anti-HIV I drugs

Francis Hubler, Thomas Rückle, Luc Patiny et al. · Tetrahedron Letters · 2000 · 38 citations

A Derivatives, Potential Anti-hiv, Medicine +9

The reversible P2Y₁₂antagonist ACT‐246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

Markus Rey, Markus Kramberg, Patrick Hess et al. · Pharmacology Research & Perspectives · 2017 · 29 citations · Full text

Conversion of cyclosporine A prodrugs in human tears vs rabbits tears

Frédéric Lallemand, O. Felt-Baeyens, Serge Rudaz et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2004 · 22 citations · Full text

Pharmaceutical Science, Human Tears, Cyclosporine A Prodrugs +7