Yuri Yanishevski

Enhanced proteolysis of thiopurine <i>S</i> -methyltransferase (TPMT) encoded by mutant alleles in humans ( <i>TPMT</i> ∗ <i>3</i> <i>A</i> , <i>TPMT</i> ∗ <i>2</i> ): Mechanisms for the genetic polymorphism of TPMT activity

Hung-Liang Tai, Eugene Y. Krynetski, Erin G. Schuetz et al. · Proceedings of the National Academy of Sciences · 1997 · 262 citations · Full text

Genetics, T-regulatory Cell, Immunology +23

Etoposide and antimetabolite pharmacology in patients who develop secondary acute myeloid leukemia

M V Relling, Yuri Yanishevski, J.F. Nemec et al. · Leukemia · 1998 · 188 citations

Hematological Malignancy, Molecular Pharmacology, Antimetabolite Pharmacology +10

Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase.

Eugene Y. Krynetski, Natalia F. Krynetskaia, Yuri Yanishevski et al. · Molecular Pharmacology · 1995 · 118 citations

Differences in Folylpolyglutamate Synthetase and Dihydrofolate Reductase Expression in Human B-Lineage versus T-Lineage Leukemic Lymphoblasts: Mechanisms for Lineage Differences in Methotrexate Polyglutamylation and Cytotoxicity

A J Galpin, John D. Schuetz, Eric Masson et al. · Molecular Pharmacology · 1997 · 117 citations

Reduced Folate Carrier Expression in Acute Lymphoblastic Leukemia: A Mechanism for Ploidy but not Lineage Differences in Methotrexate Accumulation

Vladimir M. Belkov, Eugene Y. Krynetski, John D. Schuetz et al. · Blood · 1999 · 117 citations