Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses

Saguna Verma, FuKun W. Hoffmann, Mukesh Kumar, +5

The Journal of Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyImmune RegulationImmunodominance +26

West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

Kelsey Roe, Mukesh Kumar, Stephanie Lum, +3

Journal of General Virology

Bbb PermeabilityImmunologyViral PathogenesisImmune SystemNeuroinflammation +20

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

Mukesh Kumar, Kelsey Roe, Beverly Orillo, +4

Journal of Virology

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

Mukesh Kumar, Kelsey Roe, Pratibha V. Nerurkar, +4

Journal of Neuroinflammation

West Nile Virus-Induced Cell Adhesion Molecules on Human Brain Microvascular Endothelial Cells Regulate Leukocyte Adhesion and Modulate Permeability of the In Vitro Blood-Brain Barrier Model

Kelsey Roe, Beverly Orillo, Saguna Verma

PLoS ONE

Modulate PermeabilityImmunologyViral PathogenesisImmunotherapyCerebral Vascular Regulation +15

Impaired Virus Clearance, Compromised Immune Response and Increased Mortality in Type 2 Diabetic Mice Infected with West Nile Virus

Mukesh Kumar, Kelsey Roe, Pratibha V. Nerurkar, +4

PLoS ONE

Viral PathogenesisImmunologyImmunodominanceImpaired Virus ClearanceDb/db Mouse Model +16

BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus

Daniela Giordano, Runa Kuley, Kevin E. Draves, +4

The Journal of Immunology

Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection

Jacob Nelson, Kelsey Roe, Beverly Orillo, +2

Antiviral Research

Immunotherapy StrategyImmunologyAntiviral TherapyAntiviral ResponseVirology +4

Protection of mice deficient in mature B cells from West Nile virus infection by passive and active immunization

Daniela Giordano, Kevin E. Draves, Lucy B. Young, +7

PLoS Pathogens

Adaptive Immune SystemHumoral ResponseViral PathogenesisImmunologyImmunodominance +17

STING Is Required in Conventional Dendritic Cells for DNA Vaccine Induction of Type I T Helper Cell- Dependent Antibody Responses

Justin Theophilus Ulrich-Lewis, Kevin E. Draves, Kelsey Roe, +3

Frontiers in Immunology