West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier

Saguna Verma, Yeung Y. Lo, Moti Chapagain, +6

Virology

Blood–brain BarrierVitro Blood-brain BarrierViral PathogenesisImmunologyCell Adhesion Molecules +7

Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses

Saguna Verma, FuKun W. Hoffmann, Mukesh Kumar, +5

The Journal of Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyImmune RegulationImmunodominance +26

West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

Kelsey Roe, Mukesh Kumar, Stephanie Lum, +3

Journal of General Virology

Bbb PermeabilityImmunologyViral PathogenesisImmune SystemNeuroinflammation +20

Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development.

Anne Galy, Saguna Verma, Alicia Bárcena, +1

The Journal of Experimental Medicine

Human ThymusLymphocyte DevelopmentT-regulatory CellImmunologyImmunotherapy +15

Reversal of West Nile virus-induced blood–brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor

Saguna Verma, Mukesh Kumar, Ulziijargal Gurjav, +2

Virology

Molecular VirologyNeurovirologyPathogenesisViral PathogenesisAntiviral Response +4

Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the <i>In Vitro</i> Blood-Testis Barrier Model

Daniel P. Strange, Payal N. Maharaj, Pei‐Yong Shi, +1

Journal of Virology

Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death

Mukesh Kumar, Saguna Verma, Vivek R. Nerurkar

Journal of Neuroinflammation

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

Mukesh Kumar, Kelsey Roe, Beverly Orillo, +4

Journal of Virology

Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells

Daniel P. Strange, Boonyanudh Jiyarom, Nima Pourhabibi Zarandi, +5

mBio

ACE2 receptor expression in testes: implications in coronavirus disease 2019 pathogenesis†

Saguna Verma, Sarini Saksena, Hooman Sadri‐Ardekani

Biology of Reproduction

Coronavirus Disease 2019Viral DiagnosticsSars-cov-2 InfectionPathogenesisViral Pathogenesis +9