Johanna Huttunen

l-Type Amino Acid Transporter 1 (LAT1/Lat1)-Utilizing Prodrugs Can Improve the Delivery of Drugs into Neurons, Astrocytes and Microglia

Johanna Huttunen, Soile Peltokangas, Mikko Gynther et al. · Scientific Reports · 2019 · 88 citations · Full text

L-type amino acid transporter 1 utilizing prodrugs: How to achieve effective brain delivery and low systemic exposure of drugs

Elena Puris, Mikko Gynther, Johanna Huttunen et al. · Journal of Controlled Release · 2017 · 84 citations

Utilizing Prodrugs, Neuropeptides, Medicine +10

A Selective and Slowly Reversible Inhibitor of <scp>l</scp>-Type Amino Acid Transporter 1 (LAT1) Potentiates Antiproliferative Drug Efficacy in Cancer Cells

Kristiina M. Huttunen, Mikko Gynther, Johanna Huttunen et al. · Journal of Medicinal Chemistry · 2016 · 66 citations · Full text

Chemoprevention Strategy, Lat1 Inhibitors, Pharmacotherapy +18

L-type amino acid transporter 1 utilizing prodrugs of ferulic acid revealed structural features supporting the design of prodrugs for brain delivery

Elena Puris, Mikko Gynther, Johanna Huttunen et al. · European Journal of Pharmaceutical Sciences · 2019 · 59 citations

Structural Features, Utilizing Prodrugs, Coiled-coil Drug Delivery +9

L-Type Amino Acid Transporter 1 Enables the Efficient Brain Delivery of Small-Sized Prodrug across the Blood–Brain Barrier and into Human and Mouse Brain Parenchymal Cells

Ahmed B. Montaser, Juulia Järvinen, Susanne Löffler et al. · ACS Chemical Neuroscience · 2020 · 58 citations